Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy.
Parto of the Series "Clinical Gastroenterology, Series Editor: George Y. Wu - University of Connecticut Health Center, Farmington, CT, USA. Printed by Printforce, The Netherlands. Includes 20 essays on HE, starting from the new nomenclature and classification in the last few decades, and covering the roles of ammonia, neural inflammation, general inflammation, oxidative stress, and endogenous benzodiazepines in the pathogenesis of HE, discussed by the leading authorities in these areas. 250 pages. Index pp. 245-250. With 36 b/w illustrations, both photographs and graphs, and 16 colour illustrations. Bound in blue paper on hard boards. In fine condition / as new.