A collection of fourteen papers exploring the relationships between epilepsy , psychosis and "forced normalization" (the apparent normalization of EEGs in patients with epilepsy following drug treatment), including the groundbreaking work of Heinrich Landolt (1917-1971).
Boards have very slight shelfwear. Internally unmarked, as new. xi, 235 pp; b&w illus.
The development of psychiatric problems in patients with epilepsy is not uncommon but the relationship between the two remains controversial. "Forced normalization" refers to the apparent normalization of EEGs in patients with epilepsy following drug treatment. The term was coined in the 1960s by Heinrich Landolt who noted that while EEG normalization resulted in the desired improvement of epilepsy symptoms, it was in some patients accompanied by the emergence of behavioural disturbances, or "alternative" psychoses.;Landolt's work was ignored by two generations of neurologists and psychiatrists but, with the recent introduction of powerful new anticonvulsant medications, some of which are linked with behavioural problems, his work has again become relevant. Explores the concept of forced normalization, first from a historical perspective and then from the contemporary point of view, explaining the electrophysiology and neurochemistry, and examining the implications for the modern management of epilepsy.