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Human drug metabolism

£12.00 Out Of Stock

Product description

Human Drug Metabolism, An Introduction, Second Editionprovides an accessible introduction to the subject and will beparticularly invaluable to those who already have someunderstanding of the life sciences. Completely revised and updatedthroughout, the new edition focuses only on essential chemicaldetail and includes patient case histories to illustrate theclinical consequences of changes in drug metabolism and its impacton patient welfare. After underlining the relationship between efficacy, toxicityand drug concentration, the book then considers how metabolizingsystems operate and how they impact upon drug concentration, bothunder drug pressure and during inhibition. Factors affecting drugmetabolism, such as genetic polymorphisms, age and diet arediscussed and how metabolism can lead to toxicity is explained. Thebook concludes with the role of drug metabolism in the commercialdevelopment of therapeutic agents as well as the pharmacology ofsome illicit drugs.

Item details

PLU:
0
Author(s):
Michael D. Coleman
Condition:
As new
Dimensions:
165mm x 245mm
Format:
Paperback
ISBN-10:
047074216X
ISBN-13:
9780470742167
Number of pages:
346
Publisher:
Wiley-Blackwell

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About this item

Human Drug Metabolism, An Introduction, Second Editionprovides an accessible introduction to the subject and will beparticularly invaluable to those who already have someunderstanding of the life sciences. Completely revised and updatedthroughout, the new edition focuses only on essential chemicaldetail and includes patient case histories to illustrate theclinical consequences of changes in drug metabolism and its impacton patient welfare. After underlining the relationship between efficacy, toxicityand drug concentration, the book then considers how metabolizingsystems operate and how they impact upon drug concentration, bothunder drug pressure and during inhibition. Factors affecting drugmetabolism, such as genetic polymorphisms, age and diet arediscussed and how metabolism can lead to toxicity is explained. Thebook concludes with the role of drug metabolism in the commercialdevelopment of therapeutic agents as well as the pharmacology ofsome illicit drugs.

PLU:
0
Author(s):
Michael D. Coleman
Condition:
As new
Dimensions:
165mm x 245mm
Format:
Paperback
ISBN-10:
047074216X
ISBN-13:
9780470742167
Number of pages:
346
Publisher:
Wiley-Blackwell

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This item will be dispatched to UK addresses via second class post within 2 working days of receipt of your order. Standard UK delivery is currently free no matter how many items you have in your basket. Any additional courier charges will be applied at checkout as they vary depending on delivery address.

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